Process for the manufacture of a composite material

Details Process for the manufacture of a composite material Process for the manufacture of a composite material

2008-03-03

2010-12-28

Kam, Chih-Min (Department: 1656)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

C435S041000, C530S300000, C530S329000

Reexamination Certificate

active

07858337

ABSTRACT:
The invention relates to a process for the manufacture of a composite materials comprising the steps of (a) providing a hydrophobic organic bulk material, and (b) applying a hydrophilic surface coating on the hydrophobic organic bulk material by first non-covalently attaching to the surface of the bulk material a water-soluble peptide comprising a hydrophobic moiety; and then chemically or enzymatically crosslinking the water-soluble peptide. The composite materials manufactured according to the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus particularly useful as ophthalmic devices.

REFERENCES:
patent: 4136250 (1979-01-01), Mueller et al.
patent: 2003/0175745 (2003-09-01), Dean et al.
patent: 2004/0224080 (2004-11-01), Epstein et al.
patent: 2006/0134166 (2006-06-01), Luthra et al.
patent: WO 00/18794 (2000-04-01), None
patent: WO 01/56627 (2001-08-01), None
patent: WO 2004/050132 (2004-06-01), None
PCT International Search Report, (Sep. 2008).
PCT Written Opinion of the International Searching Authority, (Sep. 2008).
European Search Report, (Sep. 2007).
Examiners Communication.

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