Process for the manufacture of a 2,3-dihydroxyquinoxaline, and 2

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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C07D24144

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049259415

ABSTRACT:
A quinoxaline is oxidized by means of hydrogen peroxide in an inert solvent medium in the presence of water and of a catalyst selected from selenium and selenium compounds.
The process applies to the preparation of substituted and unsubstituted 2,3-dihydroxyquinoxalines.

REFERENCES:
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patent: 4430502 (1984-02-01), Nelson
patent: 4628126 (1986-12-01), Drauz et al.
patent: 4812458 (1989-03-01), Honore et al.
Kirk-Othmer Encyclopedia of Chemical Technology Third Edition, vol. 20, pp. 591-593 (1982).
Newbold et al., "The Oxidation of 2--hydroxyquinoxaline and its Derivatives with Hydrogen Peroxide", Journal Chemical Society, 1948, pp. 519-522.
Landquist et al., "Derivatives of Py-Hydroxalkyl-, -Aminoalkyl-, and -Carboxy-Quinoxalines", Journal Chemical Society, 1956, pp. 1269-2572.
G. W. H. Cheeseman, "Some 2-Substituted Quinokalines", Journal Chemical Society, 1957, pp. 2845-4156.
Beilstein, Second Supplement, vol. XXIV Syst. No. 3591, pp. 380-381.
Rhone-Poulene, Chemical Abstract, vol. 84, No. 164422z (1976).

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