Process for the manufacture of 1.alpha.-hydroxydehydroepiandrost

Details Process for the manufacture of 1.alpha.-hydroxydehydroepiandrost Process for the manufacture of 1.alpha.-hydroxydehydroepiandrost

1981-08-24

1983-04-12

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435933, 435913, C12P 3306, C12R 180, C12R 166

Patent

active

043798420

ABSTRACT:
The invention relates to a process for producing 1.alpha.-hydroxydehydroepiandrosterone by fermenting or reacting dehydroepiandrosterone or a derivative thereof with microorganisms of the species Penicillium oxalicum or Aspergillus terreus or mycelium or extracts therefrom obtained when the microorganisms are in a stationary phase of growth. The invention process produces steroid compounds which are pharmacologically valuable substances.

REFERENCES:
patent: 2805231 (1957-09-01), Dodson et al.
patent: 2833793 (1958-05-01), Dodson et al.
patent: 2833794 (1958-05-01), Goldkamp et al.
patent: 4144334 (1979-03-01), Petzoldt et al.
J. Amer. Chem. Soc., vol. 79, p. 3921 (1957).

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