Process for the lowering of increased levels of cholesterol and

Details Process for the lowering of increased levels of cholesterol and Process for the lowering of increased levels of cholesterol and

1980-02-15

1981-06-09

Cacciapaglia, Jr., Frank

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 3123

Patent

active

042725488

ABSTRACT:
The present invention is related to a process for the lowering of increased cholesterol and/or increased neutral fat levels in the blood of humans by administering to such humans a completely acetylated monoglyceride having the general formula ##STR1## wherein one of the groups R.sub.1, R.sub.2 and R.sub.3 is the acyl radical of a fatty acid having from 12 to 22 carbon atoms while the other two groups represent acetyl groups, or a mixture of several such completely acetylated monoglycerides, preferably orally and in a daily dosage ranging from 1 to 15 cc. of the pure acetylated monoglyceride or mixture of such acetylated monoglycerides, either in pure form or together with usual pharmaceutical carriers or diluents, possibly together with other lipid lowering agents, or incorporated in dietetic food products.

REFERENCES:
patent: 3158541 (1964-11-01), Sutherland
patent: 3192057 (1965-06-01), Hines et al.
patent: 3203862 (1965-08-01), Jones
patent: 3388085 (1968-06-01), Levkoff et al.
patent: 3495011 (1970-02-01), Fossel
patent: 4034083 (1977-07-01), Mattson
Die Fleischwirtschaft, Apr. 1971, pp. 517-522; Dec. 1968, pp. 1594-1596; Jul. 1972, pp. 816-818.
Chem. Abstr. 88:21033v, 1978. _

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