Process for the long-term surviving culture of hepatocytes

Details Process for the long-term surviving culture of hepatocytes Process for the long-term surviving culture of hepatocytes

1989-11-15

1991-07-09

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 4, 4352401, 435240243, 43524031, C12Q 102, C12Q 100, C12N 500

Patent

active

050301055

ABSTRACT:
A process is disclosed for the long term surviving culture of hepatocytes maintaining their morphological and functional characteristics for long-term-periods, suitable to assest the acute and chronic hepatotoxicity of drugs, chemicals and environmental pollutants. The long term surviving culture of hepatocytes is carried out in a culture media containing fibroblast cells or fibroblast cell products treated to prevent cell multiplication and inoculated under controlled density.

REFERENCES:
Althaus, "Depatocyte Cultures as a Research Tool in Pharmacology and Toxicology", Vet. Pharm. Toxicol., pp. 465-478, 1983.
J. of Toxicological and Environmental Health, 26, 293-308 (1989).
Toxicology, 52, 273-286 (1988).

Affiliated with

Also associated with

Rating

Process for the long-term surviving culture of hepatocytes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the long-term surviving culture of hepatocytes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the long-term surviving culture of hepatocytes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-614706