Process for the large scale production of pituitary hormones by

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

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435241, 435948, A01N 102, C12P 2102, C12N 502

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active

042885469

ABSTRACT:
A new system of serially culturing anterior pituitary gland cells in a new nutrient medium under open aeration to produce large amounts of pituitary hormones. Using the new system of culture and new nutrient media, the pituitary cells can be grown in vitro to produce in approximately three weeks 10 to 12 times the amount of extractable hormone originally present in the original tissue.

REFERENCES:
patent: 3073746 (1963-01-01), Thompson et al.
The Merck Index-ninth edition (1976) p. 7290.
Betteridge et al.-Chem. Abst. vol. 80 (1974) p. 44148 K.

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