Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from a bark
Reexamination Certificate
2006-03-31
2008-10-14
Tate, Christopher R. (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from a bark
C424S725000
Reexamination Certificate
active
07435433
ABSTRACT:
The present invention provides an improved process for the isolation of oleane compounds from the bark ofTerminalia arjuna(Roxb.). More particularly, the present invention relates to an improved process for the isolation of arjunic acid and its derivates from the bark ofTerminalia arjuna(Roxb.). The present invention further provides the identification of arjunic acid [1] and its derivatives as anticancer agent useful in the treatment of various types of cancer in humans.
REFERENCES:
patent: 4103025 (1978-07-01), Mustich
Singh et al., “Arjunetin fromTerminalia arjunaas an insect feeding-deterrent and growth inhibitor” (2004), Phytotherapy Research, vol. 18, Issue 2, pp. 131-134.
Pelletier et al., “Separation of diterpenoid alkaloid mixtures using vacuum liquid chrmoatography” (1986), Journal of Natural Products, vol. 49 (5), pp. 892-900.
Grag Ankur
Gupta Madan Mohan
Khan Merajuddin
Khanuja Suman Preet Singh
Kumar Tiruppadiripuliyur Ranganathan Santha
Council of Scientific & Industrial Research
Dickinson Wright PLLC
Tate Christopher R.
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