Process for the isolation of chicken egg cystatin, antiviral age

Details Process for the isolation of chicken egg cystatin, antiviral age Process for the isolation of chicken egg cystatin, antiviral age

1987-10-29

1990-02-20

Moskowitz, Margaret

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

514 2, 514 12, 514 21, 530362, 530364, A61K 3548, A61K 3702

Patent

active

049025090

ABSTRACT:
There is suggested a new process for the isolation of chicken egg white cystatin from an aqueous solution of chicken egg white by means of heating to max. 80.degree. C., chromatography on carboxymethylated papain-Sepharose 4B, chromatography on Sephadex-G-50 and purification by means of ion exchange chromatrography of the Fast Protein Liquid Chromatrography type. There are further suggested new agents and methods of treating viral infections in living organisms, especially mammalian and avian picornaviral infections, by means of chicken egg white cystatin.

REFERENCES:
Schwabe, The Biochemical Journal, 217(3), 813-817, (1983).
Anastasai, The Biolochemical Journal, 211(1), 128-138, (1983).
Turk, Chem. Abst., 100, 222, (1984), Abst. No. 81820a.
Korant, Chem. Abst., 102, 445, (1985), Abst. No. 164716p.
Korant, Biochem. Biophys. Res. Commun., 127(3), 1072-1076, (1985).

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