Process for the isolation and purification of hirudin

Details Process for the isolation and purification of hirudin Process for the isolation and purification of hirudin

1990-09-27

1992-03-10

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530305, 530415, 530417, 530427, C07K 114, C07K 318, C07K 1508

Patent

active

050950924

ABSTRACT:
The invention relates to a process for the isolation and purification of hirudin from complex and salt-containing solutions by hydrophobic chromatography, using as stationary phase porous adsorber resins and as mobile phase organic solvents which are miscible with water.

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