Process for the isolation and purification of epothilones

Details Process for the isolation and purification of epothilones Process for the isolation and purification of epothilones

2005-08-17

2009-08-04

Shiao, Rei-tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S204000

Reexamination Certificate

active

07569698

ABSTRACT:
The invention relates to a desorption process for epothilones, especially epothilone A and/or epothilone B, from resins and new production, work-up or purification processes or manufacturing methods for epothilones comprising said desorption process, as well as the use of certain solvents for the desorption of epothilones from resins.

REFERENCES:
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patent: WO 98/22461 (1998-05-01), None
patent: WO 99/42602 (1999-08-01), None
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Nicolaou et al., “Probing the Ring Size of Epothilones: Total Synthesis of [14]-, [15]-, [17]-, and [18] Epothilones A,” Angew. Chem. Int. Ed., vol. 37, No. 1/2, pp. 81-84 (1998).
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