Process for the in vivo recombination of DNA sequences having mi

Details Process for the in vivo recombination of DNA sequences having mi Process for the in vivo recombination of DNA sequences having mi

1995-06-07

1999-10-12

Ketter, James

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

C12N 1564

Patent

active

059654155

ABSTRACT:
The present invention relates to a process of recombination in vivo of partially homologous DNA sequences having up to 30% of base mismatches. According to its essential characteristic, said sequences are placed together in cells or an organism of which the enzymatic mismatch repair system is defective or has been transitorily inactivated by saturation for the time to obtain recombination between said DNA sequences or in using mutants which increase the intergeneric recombination.

REFERENCES:
patent: 4863727 (1989-09-01), Zimmerman et al.
patent: 4963469 (1990-10-01), Mattes et al.
Guild, et al., Molec. Gen. Genet., vol. 128, pp. 291-300 (1974).
Tiraby, et al., J. Bacteriol., vol. 121, No. 2, pp. 608-618 (Feb. 1975).
Cummins, et al., Gene, vol. 14, pp. 263-278 (1981).
Smithies, et al., Nature, vol. 317, pp. 230-234 (Sep. 19, 1985).
Sanderson, et al., Escherichia coli and Salmonella typhimurium, 2nd Edition, pp. 1138-1144 (1987).

Affiliated with

Also associated with

Rating

Process for the in vivo recombination of DNA sequences having mi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the in vivo recombination of DNA sequences having mi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the in vivo recombination of DNA sequences having mi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-651451