Process for the immunological quantitative determination of T.su

Details Process for the immunological quantitative determination of T.su Process for the immunological quantitative determination of T.su

1990-08-17

1991-04-23

Wax, Robert A.

Chemistry: analytical and immunological testing

Thyroid hormone tests

435 78, 435 793, 435975, G01N 3353, C12Q 100

Patent

active

050100173

ABSTRACT:
The invention relates to a process for the immunological quantitative determination of the T.sub.3 and/or T.sub.4 thyroid hormones.
In a process for the immunological quantitative determination of T.sub.4 thyroxine and/or T.sub.3 triiodothyronine present in free form in a sample, T.sub.3 and/or T.sub.4 to be determined are put into competition with thyroglobulin for the sites of anti-T.sub.3 and/or anti-T.sub.4 antibodies present in a limited quantity, whereafter a determination is made of either the quantity of thyroglobulin fixed to the anti-T.sub.3 and/or anti-T.sub.4 antibodies, or the quantity of thyroglobulin not fixed to the anti-T.sub.3 and/or anti-T.sub.4 antibodies.
Application to the determination of the total T.sub.3 and/or T.sub.4 of a biological sample.

REFERENCES:
patent: 4966838 (1990-10-01), Ferrua et al.

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