Process for the hydrogenation of nitriles to primary amines

Details Process for the hydrogenation of nitriles to primary amines Process for the hydrogenation of nitriles to primary amines

1986-08-21

1988-04-19

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564415, 564448, 564490, 564491, 564492, 564493, C07C 8512

Patent

active

047391200

ABSTRACT:
An improved process is disclosed for the catalytic hydrogenation of an organic nitrile group containing compound to a primary aminomethyl group in the presence of a rhodium catalyst, a basic substance, and in a two-phase solvent system comprising an immiscible organic solvent and water.

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"Catalytic Hydrogenation in Organic Synthesis" by P. N. Rylander (1979), pp. 138 to 152, Academic Press, New York, N.Y.

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