Process for the hydrogenation of C—C double bonds

Details Process for the hydrogenation of C—C double bonds Process for the hydrogenation of C—C double bonds

2006-08-22

2006-08-22

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07094905

ABSTRACT:
The present invention relates to a gentle process for catalytic hydrogenation and to a process for the preparation of biotin using the hydrogenation step. The process according to the invention for the selective, catalytic hydrogenation of a C—C double bond on a thiazole ring system having at least one functional group which can be converted into a salt under basic conditions is characterised in that the hydrogenation is carried out in a protic solvent is a pH>7.

REFERENCES:
patent: 4792625 (1988-12-01), Wiener et al.
patent: 0570824 (1993-11-01), None
Database Crossfire Beilstein 'Online! Beilstein Institut Zur Foerderung der Chemischen Wissenschaften, Frankfurt am Main, DE; Database accession No. 852627 (reaction ID), XP002186069; Reaction Details 3; & R. J. Bonilla et al., Chem. Commun., 2000, pp. 941-942, No. 11.
Database Crossfire Beilstein 'Online! Beilstein Institut Zur Foerderung der Chemischen Wissenschaften, Frankfurt am Main, DE; Database accession No. 8678322 (reaction ID), XP002186070, & M. A. Nazareno et al., Molecules, 2000, pp. 589-590, vol. 5, No. 3.

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