Process for the evaluation of cell pictures

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36441301, G06F 1542

Patent

active

050310992

ABSTRACT:
A process and apparatus for evaluating pictures of cell cultures uses a computer-aided, observer-interactive system which records and reviews a chronological series of video pictures. The pictures are taken sequentially in each of a plurality of cell culture picture fields which border each other, each such field encompassing a different area of the specimen. Each successive chronological picture is displayed on a monitor where it is reviewed by an observer who uses a digitizing pad to apply distinguishing marks to individual cells and/or cell groups. Picture-memory-an-analysis software is used to facilitate the marking process so that observer work effort and time are remarkably reduced. Stored information relating to the position and number of the distinguishing marks applied to each chronological picture is used to generate statistical graphs and data concerning the division rate of individual cell groups, the mobility of cells, cell pedigrees, and similar matters.

REFERENCES:
patent: 4320415 (1982-03-01), Jones
patent: 4513438 (1985-04-01), Graham et al.
patent: 4700298 (1987-10-01), Palcic et al.
patent: 4724543 (1988-02-01), Klevecz et al.
patent: 4907158 (1990-03-01), Kettler et al.
"Computer-Assisted Analyses of Cell Locomotion and Chemotaxis," by P. B. Noble and M. D. Levine, published by CRC Press, Inc., Boca Raton, Florida, pp. 1, 2 and 49-76.

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