Process for the enzymatic separation of the optical isomers of a

Details Process for the enzymatic separation of the optical isomers of a Process for the enzymatic separation of the optical isomers of a

1992-04-22

1994-04-12

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435136, 435840, C12P 4100

Patent

active

053025288

ABSTRACT:
A process is described for the separation of the optical isomers of alphayl- or alpha-aryloxy- carboxylic acids by means of the stereoselective hydrolysis of racemic alkyl esters of the above acids in the presence of bacteria or their enzymes, selected from the species Brevibacterium, Bacteridium, Micrococcus, and Bacillus.

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patent: 5037751 (1991-08-01), Bertola
patent: 5077217 (1991-12-01), Matson
patent: 5108917 (1992-04-01), Bertola
Iriuchijima S, Agric Biol Chem 45:1389-92 (81).
Kato Y, Tetra Lett 28:1303-6 (87).
Sugai T, Agric Biol Chem 48:2501-4 (84).
ATCC Catalog pp. 38,64,67,70,131,132 (1989).
"The Prokayotes"; editors Balows et al, pp. I16-17 (1992).

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