Process for the enzymatic preparation of macrolactone

Details Process for the enzymatic preparation of macrolactone Process for the enzymatic preparation of macrolactone

1995-04-05

1997-01-07

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435119, 435 681, 435886, 4352535, C12P 1714

Patent

active

055916147

ABSTRACT:
This invention concerns a process for enzymatically preparing a compound of formula (1) ##STR1## from the compound of formula (2) ##STR2## by way of a microorganism or an acellular preparation derived from this microorganism. The microorganism and acellular preparation oxidizes the 2-3 bond of the macrolactones' D-proline into dehydroproline.

REFERENCES:
patent: 3137640 (1964-06-01), Watanabe
Goodfellow et al "The Biology of the Actinomycetes" 1984, p. 67-69.
Purvis et al, J. Am: Chem. Soc., 1989, vol. III, pp. 5931-5935.
Zeitschrift fur. Allg. Mikrobiologie, vol. 22, 1982, pp. 155-160.

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