Process for the dissolution of peptides in non-aqueous and mixed

Details Process for the dissolution of peptides in non-aqueous and mixed Process for the dissolution of peptides in non-aqueous and mixed

1984-06-26

1985-07-30

Schain, Howard E.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

260112R, 260112B, 2601125R, 2601127, 260113, 260121, 260122, 435198, 435213, 435219, C12H 918, C12H 920, C12H 950, C07G 700

Patent

active

045322120

ABSTRACT:
Process for the dissolution of peptides and proteins in non-aqueous and mixed non-aqueous/aqueous solvents using crown ethers, solutions thereby obtained and their use. Purification of proteins and/or enzymes, modification and optimisation of the activity of enzymes. Use of peptide-crown ether complexes as membrane materials, use of enzyme-crown ether complexes as detergents.

REFERENCES:
patent: 4156683 (1979-05-01), Lehn
H. Tsukube, "Active and Passive Transport of Amino-Acid and Oligopeptide Derivatives by Artificial Ionophore--K.sup.+ Complexes", J. Che. Soc. Perkin Trans., vol. I, (1982), pp. 2359-2363.
Synthesis, vol. 82, No. 5, pp. 412-414, Lejczak et al.
U. Olsher, "Solvation Properties of Natural and Synthetic Ionophores", Biophys. J., vol. 40, (Oct. 1982), pp. 61-68.

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