Process for the dissolution of nucleotides and polynucleotides

Details Process for the dissolution of nucleotides and polynucleotides Process for the dissolution of nucleotides and polynucleotides

1985-03-05

1988-04-19

Brown, J. R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 27, 536 28, A61K 3170, C07H 1910

Patent

active

047390450

ABSTRACT:
Process for the dissolution of nucleotides and polynucleotides in non-aqueous solvents and mixed non-aqueous solvent systems using macromolecular ligands, solutions thereby obtained and their use for the separation and purification of DNA, e.g. for RNA and protein, in the chemical synthesis of DNA, in the conversion of double stranded DNA into single stranded DNA, and in the chemical modification of DNA.

REFERENCES:
patent: 3433782 (1969-03-01), Kreiser
Pitha et al, Biochimica et Biophysica Acta, 425, (1976) 287-295.
Bose et al, J. Org. Chem., 48, (1983) 1780-1782.
Smid, Pure and Applied Chem., 54, (1982) 2129-2140.

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