Process for the determination of the toxicity preventing activit

Details Process for the determination of the toxicity preventing activit Process for the determination of the toxicity preventing activit

1985-03-01

1987-10-13

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving cholesterol

435 4, 435 29, 435 32, 436 63, 436 71, C12Q 160, C12Q 118

Patent

active

046998780

ABSTRACT:
A process for the determination of the toxicity preventing activity (TPA) of human blood serum, i.e., the effectiveness of the serum in preventing or inhibiting the destructive effect of very low density lipoproteins (VLDL) on test cells, and the use of this TPA value for classifying the serum as to atherosclerosis risk or potential. The process comprises:

REFERENCES:
Chan et al (1978), Cancer Research, vol. 38, No. 9, pp. 2958-2961.
Soutar et al (1984), Biochemical Journal, vol. 218, No. 1, pp. 101-111.
Arbogast (1982), Diabetes vol. 31, No. 7, pp. 593-599 from Chemical Abstracts (1982) p. 451, vol. 97, No. 7, item No. 53534m.
Wu et al (1979), Artery, vol. 6, No. 5, pp. 385-401, from Chemical Abstracts (1980), vol. 93, No. 5, p. 653, item No. 43290g.
Chi et al (1982), Diebetes, vol. 31, No. 12, pp. 1098-10104, from Chemical Abstracts (1983), vol. 98, No. 5, p. 524, item No. 32885g.
In vitro Injury of Porcine Aortic Edothelial Cells by Very-Low-Density Lipoproteins from Diabetic Rat Serum, "Diabetes, vol. 31, No. 7, Jul. 82".
Injury of Arterial Endothelial Cells in Diabetic, Sucrose-Fed and Aged Rats, "Atheroclerosis 51 (1984), 31-45".

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