Process for the determination of antibodies

Details Process for the determination of antibodies Process for the determination of antibodies

1991-03-01

1994-01-11

Kepplinger, Esther L.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436507, 435 71, 435 793, 530300, 5303871, 530403, 530810, 530866, G01N 33543, G01N 33564, C12Q 100, C07K 1300

Patent

active

052775895

ABSTRACT:
For the determination of antibodies based on an immunoassay technique by incubation with at least three receptors R.sub.1, R.sub.2 and R.sub.3 which are present dissolved in a liquid phase and of which R.sub.1 is an antigen which is capable of being specifically bound to the antibody to be determined, R.sub.2 mediates the binding to the solid phase and R.sub.3 carries a label, separation of the complex which forms from the solution by binding to a solid phase and measurement of the label in one of the phases, a conjugate is used as the receptor R.sub.2 composed of a receptor capable of specific binding to R.sub.1 and a substance S.sub.1, which can be specifically bound, and a conjugate of a receptor which can specifically bind to R.sub.1 and a label is used as R.sub.3, wherein the immobilization of the complex which forms is mediated by binding to a component of the solid phase which can specifically bind S.sub.1.

REFERENCES:
patent: 4659678 (1987-04-01), Forrest et al.
patent: 4661444 (1987-04-01), Li
patent: 4752638 (1988-06-01), Nowinski et al.
patent: 4792527 (1988-12-01), Uchida et al.
patent: 4870007 (1989-09-01), Smith-Lewis

Affiliated with

Also associated with

Rating

Process for the determination of antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the determination of antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the determination of antibodies will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1627508