Process for the detection of the presence of an allergy and for

Details Process for the detection of the presence of an allergy and for Process for the detection of the presence of an allergy and for

1983-03-17

1986-06-03

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 29, 435 7, C12Q 138, G01N 5300

Patent

active

045929971

ABSTRACT:
The present invention provides a process for the detection of the presence of an allergy and for the specific detection of the allergen responsible for the allergy, based on the cellular principle, wherein leukocytes of a sample to be investigated are incubated with an allergen or another stimulation factor of degranulation, such as anti-IgE, in an aqueous medium, the leukocytes are then separated off and the remaining solution is incubated with a compound of the general formula:

REFERENCES:
patent: 4016042 (1977-04-01), Svendsen
patent: 4252715 (1981-02-01), Aurell et al.
patent: 4276375 (1981-06-01), Claeson et al.
patent: 4279810 (1981-07-01), Claeson et al.
Chemical Abstracts Band 60, Nr 2, Jan. 20, 1964-Mounter et al.
J. Clin. Invest., vol. 64, Aug. 1979 (457-459; 466-475).
Clin. Chim. Acta, 32 (1971) 67-73.

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