Process for the conversion of maleic acid derivatives to their c

Details Process for the conversion of maleic acid derivatives to their c Process for the conversion of maleic acid derivatives to their c

1987-07-16

1989-06-06

Terapane, John F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

56 40, 56146, 56141, 56153, 56146, 56153, 56203, 56169, 56170, 56171, 56172, 56193, C07C 51353, C07C10200, C07C10366

Patent

active

H00006459

ABSTRACT:
A process for the isomerization of maleic acid, its monoesters and monoamides in the presence of thiourea in anhydrous conditions at elevated temperature to the corresponding fumaryl forms yields intermediates which are useful in the synthetic pathways of aspartame and other useful polypeptides.

REFERENCES:
patent: 2208519 (1940-07-01), Spence et al.
patent: 2454387 (1948-11-01), Howland et al.

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