Process for the conversion of daunorubicin into doxorubicin

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 185, C07H 1524, C07H 1500

Patent

active

050083805

ABSTRACT:
An improved process for the preparation of doxorubicin, by means of hydrolysis of a doxorubicin ester of a dicarboxylic acid, in acid medium.

REFERENCES:
patent: 3803124 (1974-04-01), Arcamone et al.
Morrison et al., Organic Chemistry, 3rd ed. (1979); p. 663, published by Allyn and Bacon, Inc.

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