Process for the continuous quaternization of tertiary amines...

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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Reexamination Certificate

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10499132

ABSTRACT:
The present invention relates to a continuous process for the quaternization of tertiary amines with an alkyl halide. The process is performed at a temperature between 50° C. and 140° C. by reacting a tertiary amine and an alkyl halide in a tubular reactor at a pressure sufficient to keep the alkyl halide dissolved in the reaction mixture. The molar ratio between the tertiary amine and the alkyl halide is from 1:1.3 to 1:2.9 and the pressure is suitably between 12 to 65 bar. The process could be performed either with or without a solvent present, preferably without a solvent. The process gives high product yields and low amounts of by-products.

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International Search Report No. PCT/EP02/13755; Completed on Mar. 27, 2003.
Abstract of EP 288857, (1988).
Abstract XP-002236250, (abstract of CN 126367A Dec. 13, 2000).

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