Process for the continuous conversion of cephalosporin derivativ

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound having a 1-thia-5-aza-bicyclo

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435 25, 435 49, 435177, 435178, 435180, 435191, 435174, 435911, C12P 3500

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052847543

ABSTRACT:
A process for the continuous conversion of cephalosporin derivatives into glutaryl-7-aminocephalosporanic acid derivatives
A process for the continuous conversion of cephalosporin derivatives into the corresponding glutaryl-7-aminocephalosporanic acid derivatives in the presence of a catalyst containing D-amino-acid oxidase is described. The product yield can be increased, where appropriate, by addition of hydrogen peroxide.

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Jong et al., ATCC Catalogue of Fungi/Yeasts, 17th ed., 1987, pp. 429, 427 and 434.
Applied Biochem & Biotech., vol. 27, Issue 3, Dey et al.
Chemical Abstracts, vol. 105, No. 3, Jul. 21, 1986, Abstract #23098P.

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