Process for the cis-selective catalytic hydrogenation of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C564S446000, C564S448000

Reexamination Certificate

active

06900355

ABSTRACT:
The invention relates to a process for the cis-selective preparation of cyclic amines of the sertralin type by reductive alkylation of cyclic imines or their precursors and catalytic hydrogenation in the presence of copper-containing catalysts and in the presence of a protic solvent.

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Cossy et al., Tetrahedron (1999) vol. 55, No. 21, p. 6483-6496.*
R. Sarges, Journal of Organic Chemistry, US, American Chemical Society, vol. 40, No. 9, (1975), pp. 1216-1224.
R.B.C. Pillai, Journal of Molecular Catalysis, vol. 84, (1993), pp. 125-129.
Dovell et al., Industrial & Engineering Chemistry Product Research and Development, Copper Chromite Catalysts for Reductive Alkylation, 1962, 1, pp. 179-181.

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