Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1987-11-20
1990-09-18
Weimar, Elizabeth C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
4352521, 435829, C12P 742, C12N 120
Patent
active
049578618
ABSTRACT:
The present invention relates to a process for the biotechnological preparation of poly-D-(-)-3-hydroxybutyric acid, herein referred to as PHB, which comprises culturing a microorganism that is a strain of Alcaligenes latus or a PHB-producing mutant thereof with unrestricted supply of nutrients, under unlimited growth conditions in the temperature range from 36.degree. to 42.degree. C. at a dissolved oxygen content of 25 to 50% of the saturation value for air and a pH value of 6.0 to 7.5. The PHB is then isolated in the customary manner from the biomass thereby obtained.
REFERENCES:
patent: 4138291 (1979-02-01), Lafferty
patent: 4786598 (1988-11-01), Lafferty et al.
Lafferty et al., Third European Congress on Biotechnology, Sep. 1984, vol. 1, No. 3, pp. 521-527.
Malik et al; "Nitrogen Fixation by the Hydrogen-Oxidizing Bacterium Alcaligens latus"; Arch. Microbial, vol. 129 (1981), pp. 254-256.
Braunegg Gerhart
Lafferty Robert M.
Dryer Mark
Patterson Jr. Charles L.
Petrochemie Danubia Ges.m.b.H.
Weimar Elizabeth C.
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