Process for the biocatalytic, correct chain folding of denatured

Details Process for the biocatalytic, correct chain folding of denatured Process for the biocatalytic, correct chain folding of denatured

1992-06-03

1994-04-12

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 693, 435 694, 435 6952, 435 696, 530402, 530351, 530397, 530344, C07K 300, C07K 1500, A61K 3702, C12P 2106

Patent

active

053025180

ABSTRACT:
Denatured recombinant fusion proteins are correctly folded in the presence of a heat shock protein which acts according to the functional principle of the bacterial GroEL or of the equivalent mitochondrial component Hsp60, and of ATP. After cleaving off the foreign sequence, biologically and medically interesting proteins are obtained in the correct conformation.

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