Process for systhesizing cyclic peptides

Details Process for systhesizing cyclic peptides Process for systhesizing cyclic peptides

1995-05-25

1997-05-27

Johnson, Jerry D.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

530333, 530338, A61K 3812

Patent

active

056333463

ABSTRACT:
A process is provided for the total synthesis of a cyclic peptide, which is useful as antifungal drug, and novel compounds prepared by the synthesis method. The cyclic peptide is represented by the following formula (I): ##STR1## wherein X1, X2, X4 and X7 are independently N-methyl-.alpha.-amino acid or .alpha.-hydroxy acid,

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