Process for synthesizing peptides - fragment condensation

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides

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530335, 530338, 530339, 530344, 530412, C07K 500

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active

053229312

ABSTRACT:
A solution phase process for making peptides having biological activity or peptide intermediates which can be used to prepare peptides having biological activity is described. The process involves the condensation reaction of two peptide fragments.

REFERENCES:
patent: 4774319 (1988-09-01), Ono et al.
patent: 4880778 (1989-11-01), Bowers et al.
Gross & Meinhofer, The Peptides, vol. 2 (Academic Press, 1980) Pp. 287-289.
M. Bodanszky, Principles of Peptide Syntheses (Springer-Verlag (1984) 208-210.
M. Bodanszky, Intl. J. Pept. Prot. Res. vol. 25 (1985) 449-474.

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