Process for synthesising peptides

Details Process for synthesising peptides Process for synthesising peptides

1985-11-22

1988-02-16

Phillips, Delbert R.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

525 541, 530334, A61K 3702, C08F28300

Patent

active

047256451

ABSTRACT:
The process enables peptides to be synthesized from amino acids with the participation of trialkylcyanosilanes.
The peptides obtained by this synthesis route are used, in particular, in pharmaceutical applications.

REFERENCES:
patent: 3988304 (1976-10-01), Gersky
patent: 4127539 (1978-11-01), Coy et al.
Chemical Abstracts, vol. 100, no. 12, Mar. 19th, 1984, p. 14, no. 86324b, Columbus, Ohio, US.
Y. Nakayama et al., "Novel Synthesis of alpha-amino acids via Cyanosilylation of Schiff Bases". Agr. Biol. Chem., vol. 39, no. 2, Feb. 1975, pp. 571-572. Edit. Agric. Chem. Soc. Tokyo, Japan.
R. L. Johnson, "Renin Inhibitors. Substitution of the Leucyl Residues of Leu-Leu-Val-Phe-OCH3 with 3-amino-2-hydroxyl-5-methylhexanoic acid" Journal of Medicinal Chemistry, vol. 25, No. 5, May 1982, pp. 605-610. American Chemical Society, US.
H. R. Kricheldorf, Liebigs Ann. Chem. 763, pp. 17-38 (1972).
Leonhard Birkofer et al., Chem. Ber, 94, pp. 1263-1267 (1961).
Leonhard Birkofer et al., Liebigs Ann. Chem., 659, pp. 190-199, (1962).
S. V. Rogozhin et al., Seriya Khimicheskaya, N. 3, pp. 657-660, (Mar. 1977).

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