Process for synthesising aminoadamantanes

Details Process for synthesising aminoadamantanes Process for synthesising aminoadamantanes

2008-07-29

2008-07-29

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S130000, C564S446000, C564S448000, C564S458000

Reexamination Certificate

active

11431175

ABSTRACT:
The present invention concerns a new process for synthesising aminoadamantanes of formula Iin which R1 and R2 are identical or different and are H or a straight or branched alkyl group comprising from 1 to 6 carbon atoms, and addition salts thereof with inorganic or organic acids, in particular memantine hydrochloride (1-amino-3,5-dimethyladamantane hydrochloride).

REFERENCES:
patent: 3391142 (1968-07-01), Mills et al.
patent: 4122193 (1978-10-01), Scherm et al.
patent: 4663481 (1987-05-01), Jones
patent: 5061703 (1991-10-01), Bormann et al.
patent: WO 2005/062724 (2005-07-01), None
patent: WO 2006/010362 (2006-02-01), None
patent: WO 2006/076560 (2006-07-01), None
patent: WO 2006/076562 (2006-07-01), None

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