Process for synthesis of proton pump inhibitors

Details Process for synthesis of proton pump inhibitors Process for synthesis of proton pump inhibitors

2006-02-21

2009-12-29

Morris, Patricia L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07638633

ABSTRACT:
A process for preparation of rabeprazole sodium comprising oxidation of wet or dry rabeprazole sulphide with sodium hypohalite in water or a mixture of water and water miscible solvent using alkali metal hydroxide and catalyst is disclosed herein. The present invention also discloses process for preparation of rabeprazole sulphide.

REFERENCES:
patent: 0268956 (1988-06-01), None
patent: WO/01/04109 (2001-01-01), None
patent: WO/2004/063188 (2004-07-01), None
PCT International Search Report for CIPLA Limited, et al., International Application No. PCT/IN2006/000077. Filed Feb. 21, 2006, Dated Oct. 3, 2006.
PCT International Preliminary Report on Patentability for CIPLA Limited, et al., International Application No. PCT/IN2006/000077. Filed Feb. 21, 2006, Dated Jul. 19, 2007.
Anonymous, Aug. 25, 2005, “Sodium Rebaprazole Preparation”, IP.com Journal, 5(9A): 20-21 (No. IPCOM000127347D).

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