Process for synthesis of heteroaryl-substituted urea...

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

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C548S251000, C548S255000, C548S262800, C548S332500, C548S371700, C548S558000

Reexamination Certificate

active

06916924

ABSTRACT:
This invention relates to novel processes for preparing heteroaryl-substituted urea compounds of formula (I):which are useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. X, Ar, L, Q andare described herein.

REFERENCES:
patent: 6080763 (2000-06-01), Regan et al.
patent: 6319921 (2001-11-01), Cirillo et al.
patent: WO 00/55139 (2000-09-01), None
patent: WO 00/55139 (2000-09-01), None
patent: WO 01/90072 (2001-05-01), None
patent: WO 01/04115 (2001-06-01), None
patent: WO 01/32627 (2001-10-01), None
International Search Report—May 7, 2002.
New Aryl/Heteroaryl C-N Bond Cross-coupling Reactions via Arylboronic Acid/Cupric Acetate Arylation Patrick Y.S. Lam, et al; Tetrahedron Letters 39, (1998) 2941-2944.
U.S. Appl. No. 09/902,085 filed Jul. 11. 2001, Kapadia, S. et al; A Novel Synthesis for Heteroarylamine Compounds.

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