Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing
Patent
1989-02-27
1990-04-03
Shaver, Paul F.
Organic compounds -- part of the class 532-570 series
Organic compounds
Silicon containing
556413, 556423, C07F 708, C07F 718
Patent
active
049142208
ABSTRACT:
A process is described for the synthesis of E-2-methyl-.alpha.,.beta.-unsaturated aldehydes, which are useful as intermediates in the synthesis of the macrolide structure of the immunosuppressant FK-506. These compounds are also useful as ultraviolet radiation absorbers.
REFERENCES:
patent: 4525586 (1985-06-01), Aristoff
patent: 4644068 (1987-02-01), Shibasaki et al.
patent: 4681951 (1987-07-01), Shibasaki et al.
J. Am. Chem. Soc., 1987, 109, pp. 5031-5033.
Tetrahedron Letters, vol. 29, No. 3, pp. 277-280, 1988.
Tetrahedron Letters, vol. 29, No. 3, pp. 281-283, 1988.
Tetrahedron Letters, No. 1, pp. 7-10, 1976.
Tetrahedron Letters, vol. 26, No. 20, pp. 2391-2394, 1985.
Recl. Trav. Chim. Pays-Bas, 10, pp. 369-370.
Tetrahedron Letters, vol. 24, No. 43, pp. 4695-4698, 1983.
J. Am. Chem. Soc., 1983, 105, pp. 646-648.
J. Org. Chem. 1986, vol. 51, pp. 5111-5123.
Desmond Richard
Mills Sander G.
Shinkai Ichiro
Volante Ralph P.
DiPrima Joseph F.
Merck & Co. , Inc.
North Robert J.
Shaver Paul F.
Winokur Melvin
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