Process for synthesis of coenzymes Q

Details Process for synthesis of coenzymes Q Process for synthesis of coenzymes Q

1975-12-12

1976-12-21

Garner, Vivian

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260462R, C07C 4973

Patent

active

039988589

ABSTRACT:
2,3-DIMETHOXY-5-METHYL-6-SUBSTITUTED-1,4-BENZOQUINONE HAVING THE FORMULA: ##STR1## in which R is ##STR2## in which S is an integer of 0 to 11 and A and B stand for hydrogen or may form a direct bond, is prepared by reacting a boric acid ester of 2,3-dimethoxy-5-methyl-1,4-benzohydroquinone with prenol or isoprenol having the above group R and subsequently reacting the resulting borate with a mild oxidant. The compound is useful as coenzyme Q and has various clinical effects.

REFERENCES:
patent: 3549668 (1970-12-01), Fukawa et al.
patent: 3657287 (1972-04-01), Kawamatsu et al.
patent: 3896153 (1975-07-01), Sato et al.

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