Process for synthesis of boric acid ester

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07F 504

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040575683

ABSTRACT:
2,3-DIMETHOXY-5-METHYL-6-SUBSTITUTED-1,4-BENZOQUINONE HAVING THE FORMULA: ##STR1## in which S is an integer of 0 to 11 and A and B stand for hydrogen or may form a direct bond,
Is prepared by reacting boric acid ester of 2,3-dimethoxy-5-methyl-1,4-benzohydroquinone with prenol or isoprenol having the above group R and subsequently reacting the resulting borate with a mild oxidant. The compound is useful as coenzyme Q and has various clinical effects.

REFERENCES:
patent: 3135782 (1964-06-01), Bengelsdorf
patent: 3215710 (1965-11-01), Hindermann et al.
patent: 3549668 (1970-12-01), Fukawa et al.
patent: 3657287 (1972-04-01), Kawamatsu et al.
patent: 3865851 (1975-02-01), Dunkerley et al.

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