Process for substituted hydrazides using carboxylic acids

Details Process for substituted hydrazides using carboxylic acids Process for substituted hydrazides using carboxylic acids

1999-08-25

2000-08-01

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544218, 546264, 564148, 564149, 564150, 564151, C07C24104, C07C24328, C07C24336, C07C24338

Patent

active

060968907

ABSTRACT:
This invention provides a convenient process for the preparation of monoacylhydrazines from carboxylic acids or their salts and hydrazine or substituted hydrazine in the presence of a 1,3,5-triazine substituted with at least one chloro or fluoro. The resulting monoacylhydrazine can further be converted to a diacylhydrazine by effectively either repeating the reaction or through reaction with a carboxylic acid chloride.

REFERENCES:
patent: 4985461 (1991-01-01), Hsu et al.
Kaminski, "2-Chloro-4,6-Disubstituted-1,3,5-Triazines A Novel Group of Condensing Reagents", Tetrahedron Letters, vol. 26 (24), 2901-2904 (1985).
Kaminski, "2-Chloro-4,6-dimethoxy-1,3,5-triazine. A New Coupling Reagent for Peptide Synthesis", Synthesis, 917-920 (1987).
Venkataraman, et al., "Cyanuric Chloride: A Useful Reagent for Converting Carboxylic Acids Into Chlorides, Esters, Amides and Peptides", Tetrahedron Letters, vol. 32, 3037-3040 (1979).

Affiliated with

Also associated with

Rating

Process for substituted hydrazides using carboxylic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for substituted hydrazides using carboxylic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for substituted hydrazides using carboxylic acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-665308