Process for stereoselectively reducing 4-aryl-4-oxobutanoic...

Details Process for stereoselectively reducing 4-aryl-4-oxobutanoic... Process for stereoselectively reducing 4-aryl-4-oxobutanoic...

2005-07-26

2005-07-26

Raymond, Richard L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C540S480000, C540S596000, C540S607000, C546S245000, C548S530000, C548S953000, C548S956000, C558S410000, C560S060000, C562S410000, C564S170000, C549S074000, C549S079000

Reexamination Certificate

active

06921822

ABSTRACT:
The present invention relates to a process for preparing stereoisomerically enriched 4-aryl-4-hydroxybutanoic acid derivatives by reducing 4-aryl-4-ketobutanoic acid derivatives in the presence of ruthenium-containing catalysts.

REFERENCES:
patent: 5420306 (1995-05-01), Noyori et al.
patent: 5763688 (1998-06-01), Ikariya et al.
patent: 5886181 (1999-03-01), Fuchs et al.
patent: 6184381 (2001-02-01), Ikariya et al.
patent: 2003/0004362 (2003-01-01), Tada et al.
Noyori, R., et al: “Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using Formic Acid-Triethylamine Mixture” Journal of the American Chemical Society, American Chemical Society, Washington, DC, US, Bd. 118,Nr. 10, 1996, Seiten 2521-2522, XP002240976 ISSN: 0002-7863 *Beispiel 2 f*.
Noyori, R. et al: “Asymmetric Transfer Hydrogenation Catalyzed by Chiral Ruthenium Complexes” Accounts of Chemical Research, American Chemical Society, Washington, US, BD. 30, Nr. 2, 1997, Seiten 97-102, XP002229949 ISSN: 0001-4842 *Seite 100—Seite 101; Beispiele 12, 13: Tabelle 1*.
Zassinovich et al. Chem Rev. 1992, 92, 1051-1069.
March, J., Advanced Organic Chemistry 4th ED John Wiley and Sons, 1992, p. 541.
Wills et al. Tetrahedron Asymmetry 1999, 2045.
Noyari et al. JACS 1996, 118, 2521-2522.
Supporting Information for Above: Noyori et al. Acc Chem Res. 1997, 30,97-102.

Affiliated with

Also associated with

Rating

Process for stereoselectively reducing 4-aryl-4-oxobutanoic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for stereoselectively reducing 4-aryl-4-oxobutanoic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for stereoselectively reducing 4-aryl-4-oxobutanoic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3376536