Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1989-06-05
1992-04-28
Naff, David M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435134, 435141, 435146, 435147, 435174, 435177, 435180, 435198, 435280, C12P 762, C12P 742, C12N 1100, C12N 920
Patent
active
051089165
ABSTRACT:
An immobilized isozyme of Lipase MY or AY from Candida rugosa is used for stereoselectively hydrolyzing racemic mixtures of esters of 2-substituted acids, other than 2-halo propionic acids, transesterifying esters or acids or esterify acids or alcohols, at high enantiomeric excess, in an organic solvent. Immobilization of the isozyme may be carried out in the presence of an organic acid such as stearic acid. The immobilized isozyme may be used with a fatty acid or fatty acid ester that increases stereoselectivity or rate of hydrolysis of a mixture of racemic esters.
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Barton Michael J.
Calton Gary J.
Cobbs Carrington S.
Goswami Animesh
Hamman John P.
Naff David M.
Rhone-Poulenc Rorer S.A.
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