Process for separation of carbohydrates

Details Process for separation of carbohydrates Process for separation of carbohydrates

1983-01-26

1983-12-20

Adee, John

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

127 34, B01D 1508

Patent

active

044216505

ABSTRACT:
There is provided a process for the separation of carbohydrates by use of hydrophobic interaction chromatography.
The process according to the present invention can accomplish effective separation of carbohydrates, particularly mucopolysaccharides including heparin, heparan sulfate, chondroitin sulfates, dermatan sulfate, hyaluronic acid, keratan sulfate and chondroitin-polysulfates. As the hydrophobic ligand in the chromatographic support to be used in the present invention, there may particularly be mentioned and alkyl group; an alkyl group substituted with a hydroxyl group, a carboxyl group and/or an amino group; an aryl group; or an aralkyl group. The chromatographic support is selected from cross-linked and non-cross-linked agaroses and polyvinyl alcohols.

REFERENCES:
patent: 3960720 (1976-06-01), Porath et al.
patent: 4076930 (1978-02-01), Ellingboe et al.
patent: 4101338 (1978-07-01), Rapaport et al.
patent: 4104078 (1978-08-01), Barker et al.

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