Process for separating stereoisomers of folinic acid

Details Process for separating stereoisomers of folinic acid Process for separating stereoisomers of folinic acid

1995-06-01

1997-02-04

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D47504

Patent

active

055999310

ABSTRACT:
The (6S) stereoisomer of folinic acid is obtained in high optical purity by salification of (R,S) folinic acid with di- or polyamines and subsequent selective crystallization of the desired diasteromeric salt.

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