Process for separating nucleic acid polymers

Details Process for separating nucleic acid polymers Process for separating nucleic acid polymers

1992-03-12

1995-08-08

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435291, 935 19, C07H 100, C07H 2102, C07H 2104

Patent

active

054400252

ABSTRACT:
A method is disclosed for separating a nucleic acid polymer without substantially denaturing the nucleic acid polymer. The method includes contacting a liquid medium, in which the nucleic acid polymer is disposed, with an electrically conductive polymer substrate. The substrate has an electrical charge which, when the substrate is contacted with said liquid medium, causes at least a portion of the nucleic acid polymer in the liquid medium to bind to said substrate without substantially denaturing the nucleic acid polymer. The substrate is then separated from the liquid medium, whereby the bound nucleic acid polymer is removed from the liquid medium, thereby isolating the bound nucleic acid polymer from the liquid medium without substantially denaturing the nucleic acid polymer.

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