Process for selectively producing 1-phosphorylated sugar...

Details Process for selectively producing 1-phosphorylated sugar... Process for selectively producing 1-phosphorylated sugar...

2006-05-02

2006-05-02

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S124000, C536S026700, C536S027110, C536S055300, C536S018500, C536S022100, C514S045000, C514S023000, C514S079000, C514S090000, C514S099000, C544S053000, C544S097000, C544S244000, C549S005000, C435S088000, C435S087000, C435S089000, C435S193000, C435S072000

Reexamination Certificate

active

07038039

ABSTRACT:
A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the equilibrium. Furthermore, using the action of a nucleoside phosphorylase, a nucleoside is prepared from the 1-phosphorylated saccharide derivative obtained and a base with improved stereoselectivity and a higher yield. This process is an anomer-selective process for preparing a 1-phosphorylated saccharide derivative and a nucleoside.

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