Combinatorial chemistry technology: method – library – apparatus – Method of screening a library – By measuring the ability to specifically bind a target...
Reexamination Certificate
2009-08-12
2011-12-27
Wessendrof, T. D. (Department: 1636)
Combinatorial chemistry technology: method, library, apparatus
Method of screening a library
By measuring the ability to specifically bind a target...
C506S007000, C506S018000, C530S326000, C536S023100
Reexamination Certificate
active
08084399
ABSTRACT:
The present invention relates to a screening method of an amphiphilic peptide specifically binding to hairpin RNA, more precisely a screening method of an amphiphilic peptide having specificity and strong binding strength to target hairpin RNA using peptide library comprising those peptides having modifications of both hydrophilic face and hydrophobic face. The method of the present invention provides a screening method of an amphiphilic peptide which is specific to hairpin RNA. So, the peptide selected by the method of the present invention can be effectively used for the study of hairpin RNA functions and for the production of a novel drug using an artificial peptide binding to a hairpin RNA target.
REFERENCES:
patent: 6358921 (2002-03-01), Kondejewski et al.
patent: 2008/0318797 (2008-12-01), Yu
Lee, Su Jin; “An Approach to the Construction of Tailor-Made Amphiphilic Peptides That Strongly and Selectively Bind to Hairpin RNA Targets”; (2009)J. Am. Chem. Soc.131(6):2224-2230.
Kieft Jeffrey
Lee Su Jin
Yu Jaehoon
Greenlee Sullivan P.C.
SNU & R&DB Foundation
Wessendrof T. D.
LandOfFree
Process for screening of a binding amphiphilic peptides... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for screening of a binding amphiphilic peptides..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for screening of a binding amphiphilic peptides... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4260256