Process for resolution of tamsulosin and compounds,...

Details Process for resolution of tamsulosin and compounds,... Process for resolution of tamsulosin and compounds,...

2005-11-15

2005-11-15

O'Sullivan, Peter (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C562S100000

Reexamination Certificate

active

06965051

ABSTRACT:
Optically impure tamsulosin including racemic tamsulosin can be resolved into optically pure (R)- or (S)-tamsulosin by the use of diastereomeric sulfonate salts of tamsulosin in a fractional crystallization technique. Racemic tamsulosin free base is a useful starting material for the resolution process and a method of obtaining the same in solid form, including two crystalline polymorphic forms, is also provided.

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patent: 290708 (2002-01-01), None
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patent: 0 257 787 (1988-03-01), None

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