Process for removing aromatic heterocyclic compounds product-con

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549392, 544 37, 546104, C07D21902, C07D31182

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active

058832564

ABSTRACT:
A process for removing aromatic heterocyclic compounds from a product-containing solution, in particular a protein solution, by bringing the solution into contact with a support material. The process is preferably carried out following a virus inactivation with acridine or acridine derivatives and makes it possible to remove these virus-inactivating agents from the solution without there being any significant product losses or changes in the biological activity of the solution.

REFERENCES:
Streitwieser, Jr. et al., "Introduction to Organic Chemistry, 3rd Ed., Chapter 31: Heterocyclic Compounds," MacMillan Publishing Company, pp. 998-999 (1985).
Park, T.H. et al.,: Isolation an fluorometric, high-perform liquid chromatographic determination of tacrine. Analytical Biochemistry vol. 159(2), pp. 358-362, 1986.
Chakrabarty, S.G. et al.: Determination of 8-MethoxyPso-ralem in Plasma by scanning fluorometry after Hinlager chromatography. Clinical Chemistry vol. 24, pp. 1155-1157, 1978. (See page 31 of CAS Search).

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