Process for refining lanolins

Details Process for refining lanolins Process for refining lanolins

1990-05-10

1992-10-13

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

554193, 554141, C09F 510

Patent

active

051552450

DESCRIPTION:

BRIEF SUMMARY
TECHNICAL FIELD

The present invention relates to a process for refining lanolins, and more particularly to a process for almost completely removing traces of pesticides from lanolin, wool grease, derivative thereof or the like to obtain highly refined lanolin or the like which is usable as a base material for cosmetics, pharmaceuticals or the like with high safety.


BACKGROUND ART

The term "lanolin" refers collectively to refined products ranging from about 36.degree. to about 44.degree. C. in melting point and obtained from wool grease (WG) which is the lipid secretion of the sebaceous glands of sheep by subjecting the grease to an acid treatment and deacidifying, decolorizing, deodorizing and like processes. Lanolin has emollient, self-emulsifying and like characteristics, closely resembles human sebum, has been dermatologically found to be of safety and has long been in prevalent use as a base material for application to the skin in the field of cosmetics, pharmaceuticals, etc. Lanolin further has a very complex composition consisting primarily of mixtures of esters of almost 100 kinds of lanolin fatty acids and more than 70 kinds of lanolin alcohols and containing up to about ten-odd % of free alcohols with sterols, several % of carbohydrates and traces of free fatty acids. It is said to be a unique lipid among other natural lipids. The lanolin fatty acids constituting lanolin (esters) include straight-chain acids in a small amount of up to about 10% of the whole amount and iso, ante-iso and like branched-chain fatty acids in an amount of about 2/3 of the whole, the remainder of about 1/3 being hydroxy fatty acids. These fatty acids range widely from 9 to 34 in the number of carbon atoms and have an average molecular weight of about 320. Further alicyclic alcohols such as cholesterol and triterpene alcohols which are predominantly lanosterol account for about 70% of all the lanolin alcohols, the balance being aliphatic alcohols chiefly including straight-chain, iso and ante-iso alcohols and further including about 5 to about 8% of diols. These alcohols range from 14 to 33 in the number of carbon atoms and about 370 in average molecular weight.
On the other hand, with the development of agricultural chemicals such as pesticides and a rapid increase in the amount of demand therefor in recent years, the raw material for lanolin, i.e., WG, contains residues of such pesticides, which are left almost unremoved by the process presently practiced for refining WG. Thus, pesticide residues are found also in the product lanolin.
The pesticide residues present in lanolin are a wide variety of pesticides which are in common use and which are divided generally into the following organic chloride compounds and organic phosphorus compounds.
Organic chlorine compounds
Hexachlorobenzene (HCB), .alpha.,.beta.,.delta.-hexachlorocyclohexane (.alpha.,.beta.,.delta.-BHC), .gamma.-hexachlorocyclohexane (.gamma.-BHC), aldrin (ALD), dieldrin (DLD), endrin (END), o,p-dichlorodiphenyltrichloroethane (o,p-DDT), p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT), p,p'-dichlorodiphenyldichloroethylene (DDE), heptachlor (HC), heptachlor epoxide (HCE), .gamma.-chlordane (.gamma.-CD), etc.
Organic phosphorus compounds
Diazinon (DZN), bromophosethyl (BPE), dichlofenthion (DCP), .alpha.-chlorfenvinphos (.alpha.-CVP), .beta.-chlorfenvinphos (.beta.-CVP), etc.
Each of the pesticides will hereinafter be referred to by the abbreviation.
Although the amounts of pesticide residues in lanolin are dependent on the WG used as the material for lanolin, especially on the history of the greasy wool from which the WG is recovered, the amounts determined by analyzing samples available were in the following ranges.


______________________________________ Amount of pesticide Pesticide Range (ppm) Average (ppm) ______________________________________ .gamma.-BHC 0-22.3 0.96 DLD 0-15 2.27 END 0-2.26 0.24 o,p-DDT 0-5.07 0.57 p,p'-DDT 0-13 1.14 DZN 0-21 17.64 DCP 0-2.24 1.25 BPE 0-2.39 1.33 .alpha.-CVP 0-7.89 3.65 .beta.-CVP 0-8.97

REFERENCES:
patent: 3853930 (1974-12-01), Richey
Diserens, Journal of Chromatography, vol. 156, #1, 1978, pp. 63-70.
Buschuyuschii et al., Chemical Abstracts, vol. 72, No. 10, 1969.
Bushuyushchii et al., Chemical Abstracts, vol. 72, No. 10, p. 109, 1970.

Affiliated with

Also associated with

Rating

Process for refining lanolins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for refining lanolins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for refining lanolins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1301887