Process for reducing the adverse taste and malodor associated wi

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514922, A61K 908

Patent

active

055763448

ABSTRACT:
The present invention is directed to a process for reducing the adverse taste and malodor associated with the H.sub.2 -antagonist nizatidine. The process involves forming an aqueous solution of the H.sub.2 -antagonist, and subjecting said solution to elevated temperatures sufficient for a period sufficient to cause a reduction in the adverse taste and/or malodor of the H.sub.2 -antagonist.

REFERENCES:
patent: 4293562 (1981-10-01), Ritter
patent: 5275823 (1994-01-01), France
patent: 5380535 (1995-01-01), Geyer et al.

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